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Upregulated miR-27a-3p Indicates a Poor Prognosis in Pancreatic Carcinoma Patients and Promotes the Angiogenesis and Migration by Epigenetic Silencing of GATA6 and Activating VEGFA/VEGFR2 Signaling Pathway

BACKGROUND: Abnormal miR-27a-3p expression has been frequently reported in several types of human cancer and contributes to tumor progression. However, the role and potential molecular mechanism of miR-27a-3p in the progression of pancreatic carcinoma have not been clarified. MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Rao, Xuefeng, Wan, Lihui, Jie, Zhigang, Zhu, Xiaoliang, Yin, Junxiang, Cao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927607/
https://www.ncbi.nlm.nih.gov/pubmed/31908490
http://dx.doi.org/10.2147/OTT.S220621