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Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease
Neutrophilia is a feature of sickle cell disease (SCD) that has been consistently correlated with clinical severity and has been shown to remain highly activated even at steady state. In addition to induction of fetal hemoglobin (HbF), hydroxyurea (HU) leads to reduction in neutrophil count and thei...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927657/ https://www.ncbi.nlm.nih.gov/pubmed/31869367 http://dx.doi.org/10.1371/journal.pone.0226583 |