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Topical Trabodenoson Is Neuroprotective in a Rodent Model of Anterior Ischemic Optic Neuropathy (rNAION)

PURPOSE: Nonarteritic anterior ischemic optic neuropathy (NAION) is the leading cause of sudden optic nerve–related vision loss currently without effective treatment. We evaluated the neuroprotective potential of ocular (topical) delivery of trabodenoson, a selective A(1) receptor mimetic, in a rode...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Mehrabian, Zara, Johnson, Mary A., Albers, David S., Rich, Cadmus C., Baumgartner, Rudolf A., Bernstein, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927734/
https://www.ncbi.nlm.nih.gov/pubmed/31879569
http://dx.doi.org/10.1167/tvst.8.6.47