VEGF/VEGFR2 signaling regulates hippocampal axon branching during development

Axon branching is crucial for proper formation of neuronal networks. Although originally identified as an angiogenic factor, VEGF also signals directly to neurons to regulate their development and function. Here we show that VEGF and its receptor VEGFR2 (also known as KDR or FLK1) are expressed in m...

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Detalles Bibliográficos
Autores principales: Luck, Robert, Urban, Severino, Karakatsani, Andromachi, Harde, Eva, Sambandan, Sivakumar, Nicholson, LaShae, Haverkamp, Silke, Mann, Rebecca, Martin-Villalba, Ana, Schuman, Erin Margaret, Acker-Palmer, Amparo, Ruiz de Almodóvar, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927742/
https://www.ncbi.nlm.nih.gov/pubmed/31868583
http://dx.doi.org/10.7554/eLife.49818