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Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling

Errorless chromosome segregation requires load-bearing attachments of the plus ends of spindle microtubules to chromosome structures named kinetochores. How these end-on kinetochore attachments are established following initial lateral contacts with the microtubule lattice is poorly understood. Two...

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Detalles Bibliográficos
Autores principales: Huis in 't Veld, Pim J, Volkov, Vladimir A, Stender, Isabelle D, Musacchio, Andrea, Dogterom, Marileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927755/
https://www.ncbi.nlm.nih.gov/pubmed/31804178
http://dx.doi.org/10.7554/eLife.49539