In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and represent a key challenge f...

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Detalles Bibliográficos
Autores principales: Williams, Iwan P., Crescioli, Silvia, Sow, Heng Sheng, Bax, Heather J., Hobbs, Carl, Ilieva, Kristina M., French, Elise, Pellizzari, Giulia, Cox, Vivienne, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Mele, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927758/
https://www.ncbi.nlm.nih.gov/pubmed/31769737
http://dx.doi.org/10.1080/19420862.2019.1685349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927758/
https://www.ncbi.nlm.nih.gov/pubmed/31769737
http://dx.doi.org/10.1080/19420862.2019.1685349

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