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In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and represent a key challenge f...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927758/ https://www.ncbi.nlm.nih.gov/pubmed/31769737 http://dx.doi.org/10.1080/19420862.2019.1685349 |