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CD4(+)FOXP3(+) Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation

Since their discovery CD4(+)FOXP3(+) regulatory T cells (Tregs) represented a promising tool to induce tolerance in allogeneic hematopoietic cell transplantation. Preclinical models proved that adoptive transfer of Tregs or the use of compounds that can favor their function in vivo are effective for...

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Detalles Bibliográficos
Autores principales: Mancusi, Antonella, Piccinelli, Sara, Velardi, Andrea, Pierini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927932/
https://www.ncbi.nlm.nih.gov/pubmed/31921162
http://dx.doi.org/10.3389/fimmu.2019.02901