WDR76 mediates obesity and hepatic steatosis via HRas destabilization

Ras/MAPK (mitogen active protein kinase) signaling plays contradictory roles in adipocyte differentiation and is tightly regulated during adipogenesis. However, mechanisms regulating adipocyte differentiation involving Ras protein stability regulation are unknown. Here, we show that WD40 repeat prot...

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Detalles Bibliográficos
Autores principales: Park, Jong-Chan, Jeong, Woo-Jeong, Seo, Seol Hwa, Choi, Kang-Yell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927951/
https://www.ncbi.nlm.nih.gov/pubmed/31873167
http://dx.doi.org/10.1038/s41598-019-56211-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927951/
https://www.ncbi.nlm.nih.gov/pubmed/31873167
http://dx.doi.org/10.1038/s41598-019-56211-6

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