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Diminished Expression of P-glycoprotein Using Focused Ultrasound Is Associated With JNK-Dependent Signaling Pathway in Cerebral Blood Vessels

MRI-guided focused ultrasound (MRgFUS) combined with microbubbles (MBs) is a promising technology that can facilitate drug delivery through a temporarily disrupted blood-brain barrier (BBB) and induce the down-regulation of P-glycoprotein (P-gp) expression on the blood vessels. Despite the increasin...

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Detalles Bibliográficos
Autores principales: Choi, HyoJin, Lee, Eun-Hee, Han, Mun, An, Sang-Hyun, Park, Juyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928061/
https://www.ncbi.nlm.nih.gov/pubmed/31920511
http://dx.doi.org/10.3389/fnins.2019.01350