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Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling

Wound healing and fibrosis following myocardial infarction (MI) is a dynamic process involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both incidence and survival rates for MI increase, management of post-MI recovery and associated complications are an increasingly imp...

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Detalles Bibliográficos
Autores principales: Rikard, S. Michaela, Athey, Thomas L., Nelson, Anders R., Christiansen, Steven L. M., Lee, Jia-Jye, Holmes, Jeffrey W., Peirce, Shayn M., Saucerman, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928129/
https://www.ncbi.nlm.nih.gov/pubmed/31920691
http://dx.doi.org/10.3389/fphys.2019.01481