Cargando…
Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling
Wound healing and fibrosis following myocardial infarction (MI) is a dynamic process involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both incidence and survival rates for MI increase, management of post-MI recovery and associated complications are an increasingly imp...
Autores principales: | Rikard, S. Michaela, Athey, Thomas L., Nelson, Anders R., Christiansen, Steven L. M., Lee, Jia-Jye, Holmes, Jeffrey W., Peirce, Shayn M., Saucerman, Jeffrey J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928129/ https://www.ncbi.nlm.nih.gov/pubmed/31920691 http://dx.doi.org/10.3389/fphys.2019.01481 |
Ejemplares similares
-
Network model‐based screen for FDA‐approved drugs affecting cardiac fibrosis
por: Zeigler, Angela C., et al.
Publicado: (2021) -
Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts
por: Nelson, Anders R., et al.
Publicado: (2023) -
Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601)
por: Almquist, Joachim, et al.
Publicado: (2020) -
Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy
por: Khalilimeybodi, Ali, et al.
Publicado: (2020) -
Toward a Multi-Scale Computational Model of Arterial Adaptation in Hypertension: Verification of a Multi-Cell Agent Based Model
por: Thorne, Bryan C., et al.
Publicado: (2011)