Caveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating and fatal disease and characterized by increased deposition of extracellular matrix proteins and scar formation in the lung, resulting from alveolar epithelial damage and accumulation of inflammatory cells. Evidence suggests that Caveolin-1 (Cav-1...

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Detalles Bibliográficos
Autores principales: Lin, Xin, Barravecchia, Michael, Matthew Kottmann, R., Sime, Patricia, Dean, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928213/
https://www.ncbi.nlm.nih.gov/pubmed/31873099
http://dx.doi.org/10.1038/s41598-019-55819-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928213/
https://www.ncbi.nlm.nih.gov/pubmed/31873099
http://dx.doi.org/10.1038/s41598-019-55819-y

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