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Modulation of Wnt/β-catenin signaling promotes blood-brain barrier phenotype in cultured brain endothelial cells

Wnt/β-catenin signaling is important for blood-brain barrier (BBB) development and is implicated in BBB breakdown under various pathophysiological conditions. In the present study, a comprehensive characterization of the relevant genes, transport and permeability processes influenced by both the aut...

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Detalles Bibliográficos
Autores principales: Laksitorini, Marlyn D., Yathindranath, Vinith, Xiong, Wei, Hombach-Klonisch, Sabine, Miller, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928218/
https://www.ncbi.nlm.nih.gov/pubmed/31873116
http://dx.doi.org/10.1038/s41598-019-56075-w