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Delayed afterdepolarization‐induced triggered activity in cardiac purkinje cells mediated through cytosolic calcium diffusion waves

Cardiac Purkinje cells (PCs) are more susceptible to action potential abnormalities as compared to ventricular myocytes (VMs), which could be associated with their distinct intracellular calcium handling. We developed a detailed biophysical model of a mouse cardiac PC, which importantly reproduces t...

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Detalles Bibliográficos
Autores principales: Shah, Chirag, Jiwani, Sohel, Limbu, Bijay, Weinberg, Seth, Deo, Makarand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928245/
https://www.ncbi.nlm.nih.gov/pubmed/31872561
http://dx.doi.org/10.14814/phy2.14296