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MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling

OBJECTIVE: MicroRNAs (miRNAs) play an integral role in maintaining beta cell function and identity. Deciphering their targets and precise role, however, remains challenging. In this study, we aimed to identify miRNAs and their downstream targets involved in the regeneration of islet beta cells follo...

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Detalles Bibliográficos
Autores principales: Mziaut, Hassan, Henniger, Georg, Ganss, Katharina, Hempel, Sebastian, Wolk, Steffen, McChord, Johanna, Chowdhury, Kamal, Ravassard, Philippe, Knoch, Klaus-Peter, Krautz, Christian, Weitz, Jürgen, Grützmann, Robert, Pilarsky, Christian, Solimena, Michele, Kersting, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928290/
https://www.ncbi.nlm.nih.gov/pubmed/31918917
http://dx.doi.org/10.1016/j.molmet.2019.11.012