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Neuronal vulnerability to fetal hypoxia-reoxygenation injury and motor deficit development relies on regional brain tetrahydrobiopterin levels

Hypertonia is pathognomonic of cerebral palsy (CP), often caused by brain injury before birth. To understand the early driving events of hypertonia, we utilized magnetic resonance imaging (MRI) assessment of early critical brain injury in rabbit fetuses (79% term) that will predict hypertonia after...

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Detalles Bibliográficos
Autores principales: Vasquez-Vivar, Jeannette, Shi, Zhongjie, Jeong, Jeong-Won, Luo, Kehuan, Sharma, Amit, Thirugnanam, Karthikeyan, Tan, Sidhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928344/
https://www.ncbi.nlm.nih.gov/pubmed/31926630
http://dx.doi.org/10.1016/j.redox.2019.101407