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Proximal esophageal contraction after induction of ineffective distal contraction by sildenafil in healthy volunteers

BACKGROUND: Proximal esophagus is composed of striated muscle replaced by smooth muscle in the distal section. Sildenafil, an inhibitor of phosphodiesterase type 5, causes a decrease in the amplitude of contractions in distal smooth muscle esophagus, with no effect on the proximal esophageal striate...

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Detalles Bibliográficos
Autores principales: Costa, Tarciana Vieira, Dantas, Roberto Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928477/
https://www.ncbi.nlm.nih.gov/pubmed/31892793
http://dx.doi.org/10.20524/aog.2019.0443