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Changes in vascular permeability in the spinal cord contribute to chemotherapy-induced neuropathic pain

Chemotherapy-induced neuropathic pain is a dose-limiting side effect of many cancer therapies due to their propensity to accumulate in peripheral nerves, which is facilitated by the permeability of the blood-nerve barrier. Preclinically, the chemotherapy agent vincristine (VCR) activates endothelial...

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Detalles Bibliográficos
Autores principales: Montague-Cardoso, Karli, Pitcher, Thomas, Chisolm, Kim, Salera, Giorgia, Lindstrom, Erik, Hewitt, Ellen, Solito, Egle, Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928576/
https://www.ncbi.nlm.nih.gov/pubmed/31669344
http://dx.doi.org/10.1016/j.bbi.2019.10.018