Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer’s disease

Systemic inflammation enhances the risk and progression of Alzheimer’s disease (AD). Lipopolysaccharide (LPS), a potent pro-inflammatory endotoxin produced by the gut, is found in excess levels in AD where it associates with neurological hallmarks of pathology. Sex differences in susceptibility to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Agostini, Alessandra, Yuchun, Ding, Li, Bai, Kendall, David A., Pardon, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928588/
https://www.ncbi.nlm.nih.gov/pubmed/31560941
http://dx.doi.org/10.1016/j.bbi.2019.09.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928588/
https://www.ncbi.nlm.nih.gov/pubmed/31560941
http://dx.doi.org/10.1016/j.bbi.2019.09.019

Ejemplares similares