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Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer’s disease

Systemic inflammation enhances the risk and progression of Alzheimer’s disease (AD). Lipopolysaccharide (LPS), a potent pro-inflammatory endotoxin produced by the gut, is found in excess levels in AD where it associates with neurological hallmarks of pathology. Sex differences in susceptibility to i...

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Detalles Bibliográficos
Autores principales:	Agostini, Alessandra, Yuchun, Ding, Li, Bai, Kendall, David A., Pardon, Marie-Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928588/ https://www.ncbi.nlm.nih.gov/pubmed/31560941 http://dx.doi.org/10.1016/j.bbi.2019.09.019

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