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A potential association between IL‐3 and type I and III interferons in systemic lupus erythematosus

OBJECTIVES: Plasmacytoid dendritic cells (pDCs), through the production of type 1 interferons (IFNs) and other cytokines, are major contributors to systemic lupus erythematosus (SLE) pathogenesis. IL‐3 promotes pDC survival, but its role in SLE is not well characterised. This study investigated seru...

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Detalles Bibliográficos
Autores principales: Oon, Shereen, Monaghan, Katherine, Ng, Milica, Hoi, Alberta, Morand, Eric, Vairo, Gino, Maraskovsky, Eugene, Nash, Andrew D, Wicks, Ian P, Wilson, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928763/
https://www.ncbi.nlm.nih.gov/pubmed/31890206
http://dx.doi.org/10.1002/cti2.1097