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Zinc Binding to Tau Influences Aggregation Kinetics and Oligomer Distribution
Metal ions are well known modulators of protein aggregation and are key players in Alzheimer’s Disease, being found to be associated to pathologic protein deposits in diseased brains. Therefore, understanding how metals influence amyloid aggregation is critical in establishing molecular mechanisms t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928861/ https://www.ncbi.nlm.nih.gov/pubmed/31783644 http://dx.doi.org/10.3390/ijms20235979 |