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Zinc Binding to Tau Influences Aggregation Kinetics and Oligomer Distribution

Metal ions are well known modulators of protein aggregation and are key players in Alzheimer’s Disease, being found to be associated to pathologic protein deposits in diseased brains. Therefore, understanding how metals influence amyloid aggregation is critical in establishing molecular mechanisms t...

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Detalles Bibliográficos
Autores principales: Moreira, Guilherme G., Cristóvão, Joana S., Torres, Vukosava M., Carapeto, Ana P., Rodrigues, Mário S., Landrieu, Isabelle, Cordeiro, Carlos, Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928861/
https://www.ncbi.nlm.nih.gov/pubmed/31783644
http://dx.doi.org/10.3390/ijms20235979