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Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells

Paracrine factors can induce cardiac regeneration and repair post myocardial infarction by stimulating proliferation of cardiac cells and inducing the anti-fibrotic, antiapoptotic, and immunomodulatory effects of angiogenesis. Here, we screened a human secretome library, consisting of 923 growth fac...

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Detalles Bibliográficos
Autores principales: Jennbacken, Karin, Wågberg, Fredrik, Karlsson, Ulla, Eriksson, Jerry, Magnusson, Lisa, Chimienti, Marjorie, Ricchiuto, Piero, Bernström, Jenny, Ding, Mei, Ross-Thriepland, Douglas, Xue, Yafeng, Peiris, Diluka, Aastrup, Teodor, Tegel, Hanna, Hober, Sophia, Sivertsson, Åsa, Uhlén, Mathias, Strömstedt, Per-Erik, Davies, Rick, Holmberg Schiavone, Lovisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928864/
https://www.ncbi.nlm.nih.gov/pubmed/31801200
http://dx.doi.org/10.3390/ijms20236037