Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins

Cadherins are a major family of cell–cell adhesive receptors, which are implicated in development, tissue homeostasis, and cancer. Here, we show a novel mechanism of post-translational regulation of E-cadherin in cancer cells by an intramembrane protease of the Rhomboid family, RHBDL2, which leads t...

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Detalles Bibliográficos
Autores principales: Battistini, Chiara, Rehman, Michael, Avolio, Marco, Arduin, Alessia, Valdembri, Donatella, Serini, Guido, Tamagnone, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928865/
https://www.ncbi.nlm.nih.gov/pubmed/31783481
http://dx.doi.org/10.3390/ijms20235958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928865/
https://www.ncbi.nlm.nih.gov/pubmed/31783481
http://dx.doi.org/10.3390/ijms20235958

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