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Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins
Cadherins are a major family of cell–cell adhesive receptors, which are implicated in development, tissue homeostasis, and cancer. Here, we show a novel mechanism of post-translational regulation of E-cadherin in cancer cells by an intramembrane protease of the Rhomboid family, RHBDL2, which leads t...
Autores principales: | Battistini, Chiara, Rehman, Michael, Avolio, Marco, Arduin, Alessia, Valdembri, Donatella, Serini, Guido, Tamagnone, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928865/ https://www.ncbi.nlm.nih.gov/pubmed/31783481 http://dx.doi.org/10.3390/ijms20235958 |
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