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mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

Phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) plays a crucial role in the control of cellular growth, proliferation, survival, metabolism, angiogenesis, transcription, and translation. In most human cancers, alterations to this pathway are common and ca...

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Detalles Bibliográficos
Autores principales: Irelli, Azzurra, Sirufo, Maria Maddalena, Scipioni, Teresa, De Pietro, Francesca, Pancotti, Amedeo, Ginaldi, Lia, De Martinis, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928935/
https://www.ncbi.nlm.nih.gov/pubmed/31766386
http://dx.doi.org/10.3390/ijms20235841