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Targeting the Oncogenic p53 Mutants in Colorectal Cancer and Other Solid Tumors

Colorectal cancer (CRC) is a kind of solid tumor and the third most common cancer type in the world. It is a heterogeneous disease characterized by genetic and epigenetic aberrations. The TP53 mutation is the key step driving the transition from adenoma to adenocarcinoma. The functional roles of TP5...

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Detalles Bibliográficos
Autores principales: Li, Hui, Zhang, Jinglin, Tong, Joanna Hung Man, Chan, Anthony Wing Hung, Yu, Jun, Kang, Wei, To, Ka Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929124/
https://www.ncbi.nlm.nih.gov/pubmed/31795192
http://dx.doi.org/10.3390/ijms20235999