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Targeting the Oncogenic p53 Mutants in Colorectal Cancer and Other Solid Tumors
Colorectal cancer (CRC) is a kind of solid tumor and the third most common cancer type in the world. It is a heterogeneous disease characterized by genetic and epigenetic aberrations. The TP53 mutation is the key step driving the transition from adenoma to adenocarcinoma. The functional roles of TP5...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929124/ https://www.ncbi.nlm.nih.gov/pubmed/31795192 http://dx.doi.org/10.3390/ijms20235999 |