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The Knockdown of TREK-1 in Hippocampal Neurons Attenuate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice

TWIK-related potassium channel-1 (TREK-1) is broadly expressed in the brain and involved in diverse brain diseases, such as seizures, ischemia, and depression. However, the cell type-specific roles of TREK-1 in the brain are largely unknown. Here, we generated a Cre-dependent TREK-1 knockdown (Cd-TR...

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Detalles Bibliográficos
Autores principales: Kim, Ajung, Jung, Hyun-Gug, Kim, Yeong-Eun, Kim, Seung-Chan, Park, Jae-Yong, Lee, Seok-Geun, Hwang, Eun Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929152/
https://www.ncbi.nlm.nih.gov/pubmed/31771312
http://dx.doi.org/10.3390/ijms20235902