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DEEPSEN: a convolutional neural network based method for super-enhancer prediction
BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929276/ https://www.ncbi.nlm.nih.gov/pubmed/31874597 http://dx.doi.org/10.1186/s12859-019-3180-z |