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DEEPSEN: a convolutional neural network based method for super-enhancer prediction

BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...

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Detalles Bibliográficos
Autores principales: Bu, Hongda, Hao, Jiaqi, Gan, Yanglan, Zhou, Shuigeng, Guan, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929276/
https://www.ncbi.nlm.nih.gov/pubmed/31874597
http://dx.doi.org/10.1186/s12859-019-3180-z