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Drug repositioning based on individual bi-random walks on a heterogeneous network

BACKGROUND: Traditional drug research and development is high cost, time-consuming and risky. Computationally identifying new indications for existing drugs, referred as drug repositioning, greatly reduces the cost and attracts ever-increasing research interests. Many network-based methods have been...

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Detalles Bibliográficos
Autores principales: Wang, Yuehui, Guo, Maozu, Ren, Yazhou, Jia, Lianyin, Yu, Guoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929332/
https://www.ncbi.nlm.nih.gov/pubmed/31874623
http://dx.doi.org/10.1186/s12859-019-3117-6