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Improving CRISPR guide design with consensus approaches
BACKGROUND: CRISPR-based systems are playing an important role in modern genome engineering. A large number of computational methods have been developed to assist in the identification of suitable guides. However, there is only limited overlap between the guides that each tool identifies. This can m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929336/ https://www.ncbi.nlm.nih.gov/pubmed/31874627 http://dx.doi.org/10.1186/s12864-019-6291-z |