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Incorporation of drug efflux inhibitor and chemotherapeutic agent into an inorganic/organic platform for the effective treatment of multidrug resistant breast cancer

BACKGROUND: Multidrug resistance (MDR) is a pressing obstacle in clinical chemotherapy for breast cancer. Based on the fact that the drug efflux is an important factor in MDR, we designed a codelivery system to guide the drug efflux inhibitor verapamil (VRP) and the chemotherapeutic agent novantrone...

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Detalles Bibliográficos
Autores principales: Dong, Yang, Liao, Hongze, Yu, Jian, Fu, Hao, Zhao, De, Gong, Ke, Wang, Qi, Duan, Yourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929438/
https://www.ncbi.nlm.nih.gov/pubmed/31870362
http://dx.doi.org/10.1186/s12951-019-0559-y