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Predicting drug-target interactions from drug structure and protein sequence using novel convolutional neural networks

BACKGROUND: Accurate identification of potential interactions between drugs and protein targets is a critical step to accelerate drug discovery. Despite many relative experimental researches have been done in the past decades, detecting drug-target interactions (DTIs) remains to be extremely resourc...

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Detalles Bibliográficos
Autores principales: Hu, ShanShan, Zhang, Chenglin, Chen, Peng, Gu, Pengying, Zhang, Jun, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929541/
https://www.ncbi.nlm.nih.gov/pubmed/31874614
http://dx.doi.org/10.1186/s12859-019-3263-x