Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium

Rationale: Exosomes are emerging as a promising drug delivery carrier. However, rapid uptake of exosomes by the mononuclear phagocyte system (MPS) remains an obstacle for drug delivery into other targeted organs, including the heart. We hypothesized that prior blocking of uptake of exosomes by the M...

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Detalles Bibliográficos
Autores principales: Wan, Zhuo, Zhao, Lianbi, Lu, Fan, Gao, Xiaotong, Dong, Yan, Zhao, Yingxin, Wei, Mengying, Yang, Guodong, Xing, Changyang, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929612/
https://www.ncbi.nlm.nih.gov/pubmed/31903116
http://dx.doi.org/10.7150/thno.38198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929612/
https://www.ncbi.nlm.nih.gov/pubmed/31903116
http://dx.doi.org/10.7150/thno.38198

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