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Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium
Rationale: Exosomes are emerging as a promising drug delivery carrier. However, rapid uptake of exosomes by the mononuclear phagocyte system (MPS) remains an obstacle for drug delivery into other targeted organs, including the heart. We hypothesized that prior blocking of uptake of exosomes by the M...
Autores principales: | Wan, Zhuo, Zhao, Lianbi, Lu, Fan, Gao, Xiaotong, Dong, Yan, Zhao, Yingxin, Wei, Mengying, Yang, Guodong, Xing, Changyang, Liu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929612/ https://www.ncbi.nlm.nih.gov/pubmed/31903116 http://dx.doi.org/10.7150/thno.38198 |
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