Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2

Bax inhibitor-1 (BI1) conveys anti-apoptotic signals for mitochondria while prohibitin 2 (PHB2) is implicated in sustaining mitochondrial morphology and function. However, their regulatory roles in acute kidney injury (AKI) are largely unknown. Methods: In human patients with AKI, levels of BI1 in u...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Zhu, Pingjun, Li, Ruibing, Ren, Jun, Zhang, Yingmei, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929616/
https://www.ncbi.nlm.nih.gov/pubmed/31903127
http://dx.doi.org/10.7150/thno.40098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929616/
https://www.ncbi.nlm.nih.gov/pubmed/31903127
http://dx.doi.org/10.7150/thno.40098

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