Matrix Metalloproteinase-sensitive Multistage Nanogels Promote Drug Transport in 3D Tumor Model

Physiological barriers inside of tumor tissue often result in poor interstitial penetration and heterogeneous intratumoral distribution of nanoparticle-based drug delivery systems (DDS). Novel, matrix metalloproteinase (MMP)-sensitive peptide-crosslinked nanogels (pNGs) as multistage DDS are reporte...

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Detalles Bibliográficos
Autores principales: Nagel, Gregor, Sousa-Herves, Ana, Wedepohl, Stefanie, Calderón, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929628/
https://www.ncbi.nlm.nih.gov/pubmed/31903108
http://dx.doi.org/10.7150/thno.34851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929628/
https://www.ncbi.nlm.nih.gov/pubmed/31903108
http://dx.doi.org/10.7150/thno.34851

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