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Matrix Metalloproteinase-sensitive Multistage Nanogels Promote Drug Transport in 3D Tumor Model
Physiological barriers inside of tumor tissue often result in poor interstitial penetration and heterogeneous intratumoral distribution of nanoparticle-based drug delivery systems (DDS). Novel, matrix metalloproteinase (MMP)-sensitive peptide-crosslinked nanogels (pNGs) as multistage DDS are reporte...
Autores principales: | Nagel, Gregor, Sousa-Herves, Ana, Wedepohl, Stefanie, Calderón, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929628/ https://www.ncbi.nlm.nih.gov/pubmed/31903108 http://dx.doi.org/10.7150/thno.34851 |
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