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A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling

Granzyme B (GrB) is an essential cytotoxic effector in cancer immunotherapy as it can be a potential biomarker to predict the efficacy of immunotherapies including checkpoint inhibitors. Monitoring the Granzyme B activity in cells would help determine a patient's clinical response to treatment...

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Detalles Bibliográficos
Autores principales: Briones, Jonathan C., Espulgar, Wilfred V., Koyama, Shohei, Yoshikawa, Hiroyuki, Park, JeongHoon, Naito, Yujiro, Kumanogoh, Atsushi, Tamiya, Eiichi, Takamatsu, Hyota, Saito, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929635/
https://www.ncbi.nlm.nih.gov/pubmed/31903110
http://dx.doi.org/10.7150/thno.37728