One in three highly selected Greek patients with breast cancer carries a loss-of-function variant in a cancer susceptibility gene

BACKGROUND: Gene panel testing has become the norm for assessing breast cancer (BC) susceptibility, but actual cancer risks conferred by genes included in panels are not established. Contrarily, deciphering the missing hereditability on BC, through identification of novel candidates, remains a chall...

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Detalles Bibliográficos
Autores principales: Fostira, Florentia, Kostantopoulou, Irene, Apostolou, Paraskevi, Papamentzelopoulou, Myrto S, Papadimitriou, Christos, Faliakou, Eleni, Christodoulou, Christos, Boukovinas, Ioannis, Razis, Evangelia, Tryfonopoulos, Dimitrios, Barbounis, Vasileios, Vagena, Andromache, Vlachos, Ioannis S, Kalfakakou, Despoina, Fountzilas, George, Yannoukakos, Drakoulis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Cancer Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929701/
https://www.ncbi.nlm.nih.gov/pubmed/31300551
http://dx.doi.org/10.1136/jmedgenet-2019-106189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929701/
https://www.ncbi.nlm.nih.gov/pubmed/31300551
http://dx.doi.org/10.1136/jmedgenet-2019-106189

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