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Ionically Cross-Linked Chitosan Nanoparticles for Sustained Delivery of Docetaxel: Fabrication, Post-Formulation and Acute Oral Toxicity Evaluation

INTRODUCTION: Polymeric nanoparticles are potential carriers for the efficient delivery of hydrophilic and hydrophobic drugs due to their multifaceted applications. Docetaxel is relatively less hydrophobic and twice as potent as paclitaxel. Like other taxane chemotherapeutic agents, docetaxel is not...

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Detalles Bibliográficos
Autores principales: Mahmood, Muhammad Ahmad, Madni, Asadullah, Rehman, Mubashar, Rahim, Muhammad Abdur, Jabar, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929931/
https://www.ncbi.nlm.nih.gov/pubmed/31908458
http://dx.doi.org/10.2147/IJN.S232350