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Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma

Muscle-invasive urinary bladder urothelial carcinoma (UBUC) is a lethal disease for which effective prognostic markers and potential therapy targets are still lacking. Previous array comparative genomic hybridization identified that 3q27 is frequently amplified in muscle-invasive UBUCs, one candidat...

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Detalles Bibliográficos
Autores principales: Wu, Wen-Ren, Lin, Jen-Tai, Pan, Cheng-Tang, Chan, Ti-Chun, Liu, Chen-Liang, Wu, Wen-Jeng, Sheu, Jim Jinn-Chyuan, Yeh, Bi-Wen, Huang, Steven K., Jhung, Jheng-Yan, Hsiao, Meng-Shin, Li, Chien-Feng, Shiue, Yow-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929993/
https://www.ncbi.nlm.nih.gov/pubmed/31903146
http://dx.doi.org/10.7150/thno.39018