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NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression

Mitochondrial dysfunction is involved in the pathogenesis of various cardiovascular disorders. Although mitochondrial dynamics, including changes in mitochondrial fission and fusion, have been implicated in the development of cardiac hypertrophy, the underlying molecular mechanisms remain mostly unk...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Zhai, Mei, Xu, Sheng, Ponnusamy, Murugavel, Huang, Yan, Liu, Cui-Yun, Wang, Man, Shan, Chan, Shan, Pei-Pei, Gao, Xiang-Qian, Wang, Kai, Chen, Xin-Zhe, Liu, Jing, Xie, Jing-Yi, Zhang, De-Yu, Zhou, Lu-yu, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929994/
https://www.ncbi.nlm.nih.gov/pubmed/31903137
http://dx.doi.org/10.7150/thno.37181