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New insights into microvascular injury to inform enhanced diagnostics and therapeutics for severe malaria

Severe malaria (SM) has high mortality and morbidity rates despite treatment with potent antimalarials. Disease onset and outcome is dependent upon both parasite and host factors. Infected erythrocytes bind to host endothelium contributing to microvascular occlusion and dysregulated inflammatory and...

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Detalles Bibliográficos
Autores principales: Erice, Clara, Kain, Kevin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930010/
https://www.ncbi.nlm.nih.gov/pubmed/31775570
http://dx.doi.org/10.1080/21505594.2019.1696621