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Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after hepatitis B vaccination

The hepatitis B (HB) vaccine effectively prevents the incidence of hepatitis B virus (HBV) infection. However, vaccine failure occurs in 5–10% of the recipients. The precise mechanisms leading to responsiveness to the HB vaccine are poorly understood. High-throughput sequencing (HTS) may help clarif...

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Detalles Bibliográficos
Autores principales: Miyasaka, Akio, Yoshida, Yuichi, Wang, Ting, Takikawa, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930056/
https://www.ncbi.nlm.nih.gov/pubmed/30945971
http://dx.doi.org/10.1080/21645515.2019.1600987