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Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

Tissue homeostasis is critically dependent on the function of tissue-resident lymphocytes, including lipid-reactive invariant natural killer T (iNKT) cells. Yet, if and how the tissue environment shapes the antigen specificity of iNKT cells remains unknown. By analysing iNKT cells from lymphoid tiss...

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Detalles Bibliográficos
Autores principales: Jimeno, Rebeca, Lebrusant-Fernandez, Marta, Margreitter, Christian, Lucas, Beth, Veerapen, Natacha, Kelly, Gavin, Besra, Gurdyal S, Fraternali, Franca, Spencer, Jo, Anderson, Graham, Barral, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930077/
https://www.ncbi.nlm.nih.gov/pubmed/31841113
http://dx.doi.org/10.7554/eLife.51663