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Recent Developments in Cell Permeable Deubiquitinating Enzyme Activity-Based Probes
Deubiquitinating enzymes (DUBs) function to remove or cleave ubiquitin from post-translationally modified protein substrates. There are about 100 known DUBs in the proteome, and their dysregulation has been implicated a number of disease states, but the specific function of many subclass members rem...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930156/ https://www.ncbi.nlm.nih.gov/pubmed/31921788 http://dx.doi.org/10.3389/fchem.2019.00876 |