Live-Cell Assays for Cell Stress Responses Reveal New Patterns of Cell Signaling Caused by Mutations in Rhodopsin, α-Synuclein and TDP-43

Many neurodegenerative diseases induce high levels of sustained cellular stress and alter a number of cellular processes. To examine how different mutations associated with neurodegenerative disease affect cell stress and signaling, we created live-cell assays for endoplasmic reticulum (ER)-mediated...

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Detalles Bibliográficos
Autores principales: Harlen, Kevin M., Roush, Elizabeth C., Clayton, Joseph E., Martinka, Scott, Hughes, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930162/
https://www.ncbi.nlm.nih.gov/pubmed/31920544
http://dx.doi.org/10.3389/fncel.2019.00535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930162/
https://www.ncbi.nlm.nih.gov/pubmed/31920544
http://dx.doi.org/10.3389/fncel.2019.00535

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